Home»Pharmaceutical Technology» Identification of phytochemicals responsible for anti-ulcer activity of acioa barteri using high performance liquid chromatography-diode array detector (HPLC-DAD)

Identification of phytochemicals responsible for anti-ulcer activity of acioa barteri using high performance liquid chromatography-diode array detector (HPLC-DAD)

 Department:Pharmaceutical Technology  
 By:usericon GodFirst  

 Project ID: 6814
 Rating:  (5.0) votes: 1
   Price:₦3000
Abstract
In this investigation, the leaf of Acioabarteri was subjected to the identification of phytochemicals responsible for the antiulcer activity of Acioabarteri using High Performance Liquid Chromatography– Diode Array Detector(HPLC-DAD). The leaf sample was extracted with ethyl acetate. Extracted sample was injected based on the retention time and peak formation, the bioactive compounds were screened. The Chromeleon 6.30 software was used to create results for the HPLC chromatograms and UV spectra of the secondary metabolites.  High Performance Liquid   Chromatography (HPLC) analysis of Acioabarterirevealed the existence of six (6) compounds which were responsible for its antiulcer activity, they are Gallic acid (1), Quercetin (2), Kaempferol (K,mpf3Orhamnoglucsid) (3), 3,4,6, tribromo-2-(2,4 dibromophenoxy)phenol (4). The chemical composition of the ethyl acetate leaf extract of Acioabarteriusing HPLC-DAD techniques shows that there are several chemicals present in good percentage, which may be responsible for the antiulcer activity of Acioabarteri. ...
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